The Vitiligo is a skin disorder of unknown cause characterized by the presence of white spots due to lack of pigmentation. Currently, there are excellent results in the best vitiligo treatment in Delhi, the fact that it is not possible to talk about cure, does not mean that there are not several therapeutic options. The patient has to believe and seek medical help for vitiligo treatment in Rohini, Pitampura.
It is a disease that affects 1% of the world population, being more frequent in those races that have a greater amount of pigmentation in the skin.
It is believed that there is a higher prevalence in women and the age of onset is between 10 and 30 years, although it can appear at any time in life.
In the indicated cases, surgical treatment is 90% effective, being a highly recommended alternative by plastic surgeon in Delhi.
What are the usual symptoms of vitiligo?
The usual symptoms of vitiligo are depigmented white spots on the skin since there are no melanocytes in these areas.
These spots are more sensitive to sunburn, so it is advisable to use sun protection.
The contrast with the pigmented areas of the skin creates a significant cosmetic problem for the patient.
What are the causes of vitiligo?
The reason why melanocytes disappear or stop synthesizing melanin is not exactly known.
Different theories have been formulated, mainly highlighting the one that considers this disease of autoimmune origin.
It has been observed that situations such as stress or trauma can precipitate the appearance of these lesions in predisposed patients.
It is sometimes associated with other types of diseases such as diabetes, pernicious anemia, Addison’s disease, or thyroid diseases.
Types of vitiligo
- The focal vitiligo is one in which macules appear isolated and reduced in size and number in any location.
- The segmental vitiligo characterized macules are unilateral and usually follow a given distribution Widespread is the most common type and is characterized by multiple hypopigmented macules dispersed throughout the body surface of symmetrical arrangement.
- The acrofacial Vitiligo affects distal parts and facial region. The universal form is one in which few pigmented areas of the body remain.
How is vitiligo diagnosed?
The diagnosis is established in most cases by clinical examination of the patient’s skin.
Sometimes you can use the Wood or Slit Lamp. This is an ultraviolet light that makes areas without melanocytes appear bright white.
Sometimes a skin biopsy must be performed to rule out other autoimmune diseases, as well as blood tests with determination of thyroid hormones or vitamin B12.
How is vitiligo treated?
Conservative Vitiligo Treatment in Delhi
In limited areas, potent corticosteroids can be used, but always avoiding continuous chronic application.
When it comes to more extensive vitiligo, what is known as oral photochemotherapy is usually used, which consists of the administration of an oral drug (psoralen) plus exposure to UVA rays (PUVA). Repigmentation is achieved on occasions in 50% of cases.
Another type of vitiligo treatment in Rohini used in moderately spread vitiligo is the application of Kellina topically plus sun exposure. Never more than half an hour. The administration of amino acids such as phenylalanine both orally and topically accompanied by sun exposure, is another of the therapeutic modalities used in vitiligo.
Good results have also been obtained with topical calcipotriol, which is a drug used in psoriasis, and with calcineurin inhibitors.
Surgical Vitiligo Treatment in Delhi
Lately there are more and more publications about the surgical vitiligo treatment in Pitampura, through the use of autologous skin grafts or selective melanocyte cultures.
This new technique consists of transplanting the patient’s own epidermal cells (skin cells) from a pigmented area to certain areas that appear depigmented.
In general, this cell therapy technique has been applied in those areas where a more satisfactory response is expected, such as the facial region, which is also the one that most often interests affected people. There are other areas of the body where repigmentation is not so good, such as the hands, where the appearance of vitiligo is also frequent.
The best indication is the vitiligo treatment of selective areas, not large areas, that remain stable and have not responded to conventional medical vitiligo treatment in Delhi.
It is important to note that surgical vitiligo treatment in Rohini, Pitampura using epidermal cell sheets should never be a first-line treatment for vitiligo and should never be applied to active vitiligo.
Finally, in those patients where the vitiligo areas are greater than those of the normal pigmented skin, the treatment may consist of the depigmentation of healthy skin using topical hydroquinone at high concentrations.
Cell Therapy For Stable Vitiligo
The cell therapy for the vitiligo treatment in Pitampura, Rohini is a technique that begins with the cultivation of epidermal cells, mixture of keratinocytes and melanocytes, then proceed with selective cultures, so that they form a monolayer on the support amniotic membrane.
The procedure developed by a team of specialists from the Clinic, begins with obtaining a biopsy (small skin surface) extracted from a hidden area, such as the lumbar region or the buttock, which is pigmented.
Next, the skin sample is processed in the Cell Therapy area. There, enzymatically, they separate the epidermis from the dermis to obtain, from the already disintegrated epidermis, the cells necessary for cultivation.
The cell units obtained are then cultured on an amniotic membrane until millions of cells have grown.
The amounts of epidermal cells obtained from the culture should be processed until enough cell surface is achieved to cover the affected area. If the area to be treated is very large, it will be necessary to increase the number of weeks that the epidermal cells must remain in culture. In this way, as many plates of cells as required by the affected area are obtained.
The application of the amniotic membranes with the epidermal cells in the patient is carried out in the operating room:
- First, the white spots are treated with a CO2 laser. It is necessary to apply the laser in a very superficial way to get rid of the epidermis.
- The amniotic membranes with the epidermal cells are then implanted on this epidermis.
- Once transplanted, the layers of melanocytes must be covered with an occlusive dressing that will lift after 3 or 4 days.
- Next, the patient should be exposed to solar ultraviolet radiation, if it is a suitable time of year, or UVA rays, following a specific protocol.
The surgical technique is ambulatory and is performed under local anesthesia.
In general, this cell therapy technique has been applied in those areas where a more satisfactory response is expected, such as the facial region, which is also the one that most often interests affected people. There are other areas of the body where repigmentation is not so good, such as the hands, where the appearance of vitiligo is also frequent.
